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      <image:title>Washington University in Saint Louis</image:title>
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      <image:title>The WISTAR - MD Anderson - Penn</image:title>
      <image:caption>Figure 1. Patients’ treatment history prior to surgery for PDX generation. While the majority of patients were treatment-naïve, up to 50 patients per category who received prior therapy relapsed after initial responses. Specimens derived from patients who relapsed on BRAF or BRAF/MEK inhibitor therapy were grown as PDX in the presence of the respective inhibitors. Targeted therapy (TT;) immune checkpoint inhibitors (IT;) sequential therapies (Seq); combination therapies (Combo).</image:caption>
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